Our papers on using network biology to engineer cell fate were recently published back-to-back in the August 14 issue of Cell.
- Morris SA*, Cahan PC*, Li H*, Zhao A, San Roman AK, Shivdasani RA, Collins JJ, Daley GQ. Dissecting Engineered Cell Types and Enhancing Cell Fate Conversion via CellNet. Cell. 2014 Aug 14;158(4):889-902. * Equal contribution.
- Cahan PC*, Li H*, Morris SA*, Lummertz da Rocha E, Daley GQ, Collins JJ. CellNet: Network Biology Applied to Stem Cell Engineering. Cell. 2014 Aug 14;158(4):903-15. * Equal contribution.
We were also very happy that our artwork was selected as the cover image: http://www.cell.com/cell/issue?pii=S0092-8674%2814%29X0017-6
The cover depicts an adaptation of the Boston subway system map in which subway lines represent pathways of differentiation from pluripotent stem cells. Bus routes, shown as dashed lines, are the various ways that cells can be experimentally interconverted via directed differentiation, direct conversion, and reprogramming.